CONTRIBUTION OF RESIDENT MEMORY CD8+ T CELLS TO PROTECTIVE IMMUNITY AGAINST RESPIRATORY SYNCYTIAL VIRUS AND THEIR IMPACT ON VACCINE DESIGN

Contribution of Resident Memory CD8+ T Cells to Protective Immunity against Respiratory Syncytial Virus and Their Impact on Vaccine Design

Worldwide, human respiratory syncytial virus (RSV) is the most common etiological agent for acute lower respiratory tract infections (ALRI).RSV-ALRI is the major cause of hospital admissions in young children, and it can cause in-hospital deaths WHITE QUINOA in children younger than six months old.Therefore, RSV remains one of the pathogens deemed

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Case Report: Interest of Positron Emission Tomography in Pediatric Small Vessel Primary Angiitis of the Central Nervous System

Primary angiitis of the central nervous system (PACNS) is a rare inflammatory disease affecting central nervous system vessels.The diagnosis, which requires confirmation by brain biopsy, Connect IR remains challenging due to unspecific clinical presentation and low specificity of imaging and laboratory exams.In these two pediatric biopsy-proven cas

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Loss of Mfn1 but not Mfn2 enhances adipogenesis.

ObjectiveA biallelic missense mutation in mitofusin 2 (MFN2) causes multiple symmetric lipomatosis and partial lipodystrophy, implicating disruption of mitochondrial fusion or interaction with other organelles in adipocyte differentiation, growth and/or survival.In this study, we aimed to document the impact of loss of mitofusin 1 (Mfn1) or 2 (Mfn2

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